Effects of daidzein on proliferation and differentiation of cultured osteoblasts in vitro
Abstract
Object To study the effects of Daidzein on proliferation and differentiation of cultured osteoblasts in vitro. Methods MTT and RIA were used separately to observe the proliferation and the comcentration of BGP outside the osteoblasts cultured in vitro with Daidzein of different concentration in it for different incubation periods.Protein was measured by Lowry.Results It was found that Daidzein had the effects on promoting proliferation of osteoblasts cultured for 48 h and 72 h at doses ranging from 1×10 -9 mol/L～1×10 -5 mol/L,The concentration of BGP was increased by Dzidzein at doses ranging from 1×10 -9 mol/L～1×10 -7 mol/L after 48 h and 72 h incubation.Conclusion Daidzein has the effects on stimulating the proliferation and differentiation of cultured osteoblasts in vitro.
Read the paper
Related studies
- Irisin Enhances Osteoblast DifferentiationIn Vitro
- Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo
- Interaction between Schwann Cells and Osteoblasts In Vitro
- Administration of cinnamaldehyde promotes osteogenesis in ovariectomized rats and differentiation of osteoblast in vitro
- The Effect of the Major Components of Fructus Cnidii on Osteoblasts In Vitro
- Estrogen depletion alters osteogenic differentiation and matrix production by osteoblasts in vitro
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.