Advance in differentiation of embryonic stem cells into osteoblasts in vitro
Abstract
OBJECTIVE: To review the progress, methods and obstacles in the differentiation of embryonic stem cells (ESCs) into osteoblasts in vitro. METHODS: The recent literature concerned with the differentiation of ESCs into the osteoblasts was extensively reviewed and briefly summarized. RESULTS: ESCs was a good tool for derivation of obsteoblasts. CONCLUSION: The study on the induction of ESCs into the osteogenic lineage provides a model for analyzing the molecular processes of osteoblasts development in vivo and establishes the foundation for the use of ESCs in skeletal tissue repair.
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