Central serous chorioretinopathy in patients receiving exogenous testosterone therapy
Abstract
PURPOSE: To report an association between central serous chorioretinopathy (CSCR) and exogenous testosterone therapy.
METHODS: This is a retrospective case series from two institutions. Patients who presented with fluorescein angiography and optical coherence tomography findings consistent with CSCR were included. All patients were concurrently being treated with exogenous testosterone therapy and lacked other known risk factors for CSCR.
RESULTS: Nine patients presented with CSCR after beginning exogenous testosterone therapy. Two patients stopped therapy with resolution of symptoms and subretinal fluid.
CONCLUSION: Exogenous testosterone may be an independent risk factor for the development of CSCR.
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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