Testosterone and depression in men
Abstract
Researchers at Harvard University recently conducted a study to compare levels of testosterone among HIV-positive men who had HIV-related weight loss. The researchers also gave some subjects injections of testosterone to find out if supplements of this hormone had an impact on feelings of depression. The researchers found that men who had low levels of testosterone were more likely to be depressed than men who had normal levels of this hormone. Moreover, when the depressed men received regular injections of testosterone their mood significantly improved.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.
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