Testosterone, 5 alpha-dihydrotestosterone and cortisol in men with and without alcohol-related aggression
Abstract
OBJECTIVE: The present investigation was designed to study steroid hormones, alcohol and aggression interactions in men with a history of alcohol-related aggression (AGG+) and in a cross-sectional control population (AGG-).
METHOD: AGG+ (n = 40) and AGG- (n = 44) male volunteers completed the Buss-Perry Aggression Questionnaire and the revised Michigan Alcoholism Screening Test (MAST), after which plasma-free and total testosterone, 5alpha-dihydrotestosterone (DHT) and cortisol were determined.
RESULTS: The AGG+ men displayed significantly (p < .05) higher aggression and MAST measures compared with the AGG- men; however, no significant group differences were observed regarding the hormone values. Independently of the steroid hormones, MAST correlated positively with the hostility subscale in both AGG- and AGG+ groups. Free and total testosterone correlated positively with anger and DHT correlated positively with verbal aggression and anger, whereas cortisol correlated negatively with physical aggression and anger in the AGG- group. No significant correlations between steroid hormones and aggression parameters were observed in the AGG+ group. The age factor explained part of the MAST and steroid hormone correlations with aggression. A hormone and MAST independent moderation effect of age upon aggression was also found.
CONCLUSIONS: The present study demonstrates an association between alcohol drinking and self-reported sober-state aggression, which implies that the etiology…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 44 participants or records.
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