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Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy

Dhurat R, Mathapati S

Indian journal of dermatology, 2015

Abstract

INTRODUCTION: The efficacy of conventional therapy viz. finasteride and minoxidil in androgenetic alopecia (AGA) that is based on both preventing hair loss and promoting new hair growth, varies between 30% and 60%. This has led to a large number of patients unsatisfied who demand for a better cosmetic coverage over the scalp. Microneedling has recently been reported to be promising, effective and a safe treatment modality in the treatment of AGA. This augments the response of conventional therapy.

MATERIALS AND METHODS: Four men with AGA were on finasteride and 5% minoxidil solution since 2 to 5 years. Though there was no worsening in their respective AGA stages with the therapy, they showed no new hair growth. They were subjected to microneedling procedure over a period of 6 months along with their ongoing therapy. Patients were assessed with the use of the standardized 7-point evaluation scale and patients' subjective hair growth assessment scale. The patients were followed up for 18 months post microneedling procedure to assess the sustainability of the response.

RESULTS: All patients showed a response of + 2 to + 3 on standardized 7-point evaluation scale. The response in the form of new hair growth started after 8-10 sessions. The patients' satisfaction was more than 75% in three patients and more 50% in one patient, on patients' subjective hair growth assessment scale. The obtained results were sustained post procedure during 18 months follow-up period.

CONCLUSION:…

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