The use of MRI in the pre-surgical evaluation of patients with androgen insensitivity syndrome
Abstract
BACKGROUND: Patients diagnosed with androgen insensitivity syndrome (AIS) need bilateral gonadectomy (orchiectomy) for malignancy risk reduction. Imaging of the gonads (testicles) prior to surgery is recommended. Ultrasonography has typically been used. However, magnetic resonance imaging (MRI) provides better localization of the gonads and pre-surgical planning.
CASES: In this case series, we describe how MRI was utilized in planning surgical gonadectomy in 3 patients with complete AIS and to review the literature regarding MRI and AIS.
SUMMARY AND CONCLUSIONS: MRI prior to surgery was helpful in localizing and planning for removal of the gonads while preventing injury to other structures. Surgical specialists with experience with inguinal dissection were appropriately consulted when an inguinal dissection was likely to be needed to complete the gonadectomy.
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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