Effects of dimethylnitrosamine on some actions of testosterone
Abstract
Using homogenates of mouse kidney and testes, the activities of the enzymes, beta-glucuronidase and beta-galactosidase, were studied as markers of androgen action. The results obtained differed between testes and kidney homogenates. Dimethylnitrosamine (DMN) may cause a competitive inhibition of the anabolic action of testosterone in kidney homogenates but this was not evident from the results obtained with testes homogenates.
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