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Psychological Activity Study and In vitro Interaction of Azithromycin with Empagliflozin and Investigation of Antimicrobial Activity

S. Jannat, Sumaiya Saofa, Saima Sultana Alam, M. Islam

Pharmaceutics and Pharmacology Research, 2025

Abstract

Azithromycin is used to treat or prevent certain bacterial infections, most often those causing middle ear infections, strep throat, pneumonia, typhoid, bronchitis, and sinusitis. In recent years, it has been used primarily to prevent bacterial infections in infants and those with weaker immune systems. Azithromycin and Empagliflozin commonly prescribed medications for the treatment of various medical conditions, including bacterial infections and type 2 diabetes, respectively. It should be mentioned that Azithromycin and Empagliflozin have no significant Psychological activity. The co-administration of these drugs is not uncommon, particularly in patients with comorbidities. However, concerns regarding potential drug interactions and their impact on safety and efficacy have arisen in clinical practice. This research paper explores the interaction between Azithromycin and Empagliflozin. An in-depth analysis was conducted through in-vitro studies. The primary objectives were to assess whether Empagliflozin has the potential to influence the pharmacokinetics of Azithromycin. The results revealed that Azithromycin can indeed interact with Empagliflozin. These findings suggest that the concurrent use of Azithromycin and Empagliflozin may necessitate dose adjustments or close monitoring to maintain therapeutic efficacy. Understanding the interaction between Azithromycin and Empagliflozin is crucial for optimizing patient care and ensuring the safe and effective management of…

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