Low skeletal bone mineral density as a potential aetiological factor towards idiopathic condylar resorption
Abstract
The aim of this study was to investigate the contributing factor of impaired skeletal quality in the pathogenesis of idiopathic condylar resorption (ICR). One hundred and twenty-six patients with MRI-confirmed ICR and 596 patients with disc displacement (DD) without a diminished condyle, of both sexes, were included. Dental examinations and retrospective surveys regarding temporomandibular joint symptoms and progression of maxillofacial deformities were conducted. Skeletal bone mineral density (BMD) was measured by dual energy X-ray absorptiometry (DXA) and converted to T-scores and Z-scores. Results showed that ICR patients had a smaller overbite (1.56±3.3 vs 3.05±2.0mm), larger overjet (4.9±2.4 vs 3.5±1.9mm), larger range of mouth opening (36.5±6.7 vs 33.6±7.1mm), and higher rates of anterior open bite and mandibular retrusion compared to DD patients (all P<0.001). ICR was associated with an increased probability of low skeletal BMD at chronological age in females (P=0.020) but not in males (P=0.095). This study indicates that reduced BMD may predispose females to an exacerbated condylar resorption process in addition to increased joint loading initiated from DD.
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 596 participants or records.
Read the paper
Related studies
- Development of a crushable foam model for human trabecular bone
- Data-driven motion compensation in HR-pQCT.
- Modeling of structure, quality, and function in the orthodontic patient
- Exploring the mechanism of Heidihuang Pill in the treatment of osteoporosis based on network pharmacology, molecular docking, and experimental validation
- Effect of fabric on the accuracy of computed tomography-based finite element analyses of the vertebra
- Use of interventions involving virtual reality tasks during the climacteric: a systematic review
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.