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Reduction of bone mineral density in native Chinese female idiopathic benign paroxysmal positional vertigo patients

Wu Y, Gu C, Han W, Lu X, Chen C, Fan Z

American journal of otolaryngology, 2018

Abstract

OBJECTIVE: This study aimed to investigate the clinical association between idiopathic benign paroxysmal positional vertigo (BPPV) and reduction of bone mineral density (BMD).

METHODS: BMD was measured in 78 native Chinese female de novo idiopathic BPPV patients and 126 healthy controls using dual-energy X-ray absorptiometry. We compared the mean T-scores and abnormal BMD prevalence between the two groups.

RESULTS: The mean T-scores were significantly lower in idiopathic BPPV patients than in healthy controls. The prevalence of osteopenia and osteoporosis were significantly higher in idiopathic BPPV patients than in healthy controls (65.4% vs 48.4%, p=0.013).

CONCLUSION: BMD reduction may be associated with idiopathic BPPV occurrence.

How strong is the evidence?

Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.

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