Bone Mineral Content and Density in Indian Children with Congenital Adrenal Hyperplasia
Abstract
OBJECTIVE: To study the bone mineral content and density in children with congenital adrenal hyperplasia (CAH).
METHODS: 35 children with congenital adrenal hyperplasia and 35 healthy controls. Bone mineral content and density were studied by Dual Energy X-ray absorptiometry.
RESULTS: The mean (SD) of lumbar spine bone mineral density (g/cm2) [0.590 (0.100) vs 0.589 (0.088) (P=0.97)], total Body less head bone mineral density (g/cm2) [0.536 (0.090) vs 0.548 (0.111) (P=0.64)], lumbar spine bone mineral content (g) [29.85 (27.63) vs 31.03 (29.19) (P=0.86)], and total body less head bone mineral content (g) [254.27 (281.25) vs 273.07 (330.71) (P=0.79)] were not different between children with CAH and controls, respectively.
CONCLUSIONS: Bone mineral density and content in children with congenital adrenal hyperplasia are maintained in the normal range.
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 35 participants or records.
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