The association between dietary mineral intake and bone mineral density: a cross-sectional study
Abstract
OBJECTIVES: Minerals are essential for maintaining bone health; however, the relationship between specific mineral intakes and bone mineral density (BMD) remains insufficiently understood. This study aims to examine the associations between the intakes of dietary minerals, including calcium (Ca), phosphorus (P), magnesium (Mg), iron (Fe), zinc (Zn), copper (Cu), sodium (Na), potassium (K), and selenium (Se), and BMD.
METHODS: A cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey (NHANES). Multivariate weighted generalized linear regression and smooth curve fitting were applied to evaluate the associations between dietary mineral intakes and BMD. Furthermore, subgroup analyses and interaction tests were performed to assess the consistency of these associations across different individual characteristics.
RESULTS: A total of 11,520 representative adult participants were included in the study. Tertile-based categorical analysis revealed significant positive correlations between the intakes of Ca [β: 0.0096, 95% Confidence Interval (95% CI): (0.0001, 0.0192)], Mg [β: 0.0207, 95% CI: (0.0107, 0.0307)], Fe [β: 0.0157, 95% CI: (0.0061, 0.0253)], Zn [β: 0.0106, 95% CI: (0.0020, 0.0192)], Cu [β: 0.0088, 95% CI: (0.0000, 0.0176)], Na [β: 0.0126, 95% CI: (0.0024, 0.0228)], and Se [β: 0.0123, 95% CI: (0.0024, 0.0221)] and BMD (all P < 0.05). Smooth curve fitting and threshold effect analyses further demonstrated nonlinear…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 11,520 participants or records.
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