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PB1502 Hemostatic Imbalance Associated with Tamoxifen in Estrogen Receptor-Positive Breast Cancer Patients: An Observational Study

Marie Didembourg, Sara Reda, J. Oldenburg, Heiko Rühl, Jonathan Douxfils, Laure Morimont

Research and Practice in Thrombosis and Haemostasis, 2023

Abstract

Estrogen use in this transgender cohort was frequent, and although not significantly associated with CTE, a trend towards higher risk was observed. Even in young transgender women, addressing modifiable cardiovascular risk factors should be a critical priority. Prospective studies are needed to better understand the intrinsic risks of this population and risk reduction strategies.

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Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

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