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The effect of radiopharmaceutical incubation time on bone scan quality

Henkin RE, Woodruff A, Chang W, Green AM

Radiology, 1980

Abstract

Clinical variability in the quality of bone scans led to an evaluation of the effect of incubation time on the bone scanning agent as it affects the background quality of the scan. Results of the study suggest that an incubation time of 30 minutes produces optimal bone to soft-tissue ratios with 99mtechnetium methylene diphosphonate.

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Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

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