Pseudopermeative skeletal lesions
Abstract
Permeative bone lesions are well known to radiologists and usually invoke a differential diagnosis that includes aggressive lesions such as round cell malignancies and infection. In contrast to permeative lesions, which demonstrate multiple small holes at the endosteal surface of the cortex secondary to a medullary process, we describe a series of 19 patients (seven with aggressive osteoporosis, eight with prior radiation therapy and four with hemangiomas) who demonstrated multiple tiny lucencies in the cortex which were superimposed on the medullary space and mimicked a permeative pattern radiographically. We termed this a pseudopermeative pattern. Recognition of a pseudopermeative pattern may allow a less sinister differential diagnosis to be considered and may avert unnecessary biopsy in many instances.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 19 participants or records.
Read the paper
Related studies
- Benign periarticular, bone and joint lipomatous lesions
- A review of the physiological and histological effects of laser osteotomy
- Quality of bone healing: perspectives and assessment techniques
- Effects of bioactive lipids and lipoproteins on bone
- Bone structure and function
- Quantifying bone structure, micro-architecture, and pathophysiology with MRI.
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.