True osseous metaplasia of the endometrium: the bone is not from a fetus
Abstract
OBJECTIVE: To identify the origin of calcified tissue in endometrial ossification.
DESIGN: DNA analyses from the ossified tissue and from the woman were studied to compare both genotypes.
SETTING: University and general hospitals.
PATIENT(S): A 27-year-old infertile woman diagnosed of osseous metaplasia of the endometrium.
INTERVENTION(S): Hysteroscopic resection of the endometrial osseous metaplasia for DNA analysis.
MAIN OUTCOME MEASURE(S): DNA comparison between the patient and the osseous tissue extracted from the uterus.
RESULT(S): All markers produced the same allele length for both blood and endometrial biopsy (including bones), thus confirming the same genetic origin.
CONCLUSION(S): Endometrial ossification is derived from the patient, resulting in a true osseous metaplasia.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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