TRP channels and mechanical stress
Abstract
Transient receptor potential (TRP) channels respond to diverse external stimuli and convert them into intracellular calcium signals. Recent evidence shows that TRPV4, one of the vanilloid subfamily, plays a key role in mechanosensation in bone. Here I summarize the current knowledge on possible functions of TRP channels.
How strong is the evidence?
Evidence Hub reads this as a review, done in animal, not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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