Pharmacotherapy of Type 2 Diabetes Mellitus
Abstract
This book chapter provides a comprehensive and comparative overview of available pharmacotherapy options for the management of type 2 diabetes mellitus (T2DM). With the increasing prevalence of T2DM worldwide, it is important to understand the effectiveness of all available options for adequate glycemic control and prevention of long-term complications. The chapter begins with a comprehensive overview on different aspects of T2DM, with special attention to details on different pharmacotherapeutic options available for its management. The role of newer antidiabetic medications such as sodium-glucose transporter 2 (SGLT2) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonist, bile acid sequestrant, and dual GIP/GLP-1 receptor agonist is also emphasized. Additionally, formulations and usage of insulin and non-insulin injectables have been compared. Moreover, the current trends in management of T2DM and drugs in pipeline have also been discussed briefly. In conclusion, this book chapter provides a complete overview along with comparison of oral as well as injectable antidiabetic agents used for the management of T2DM. The healthcare professional will be equipped with the knowledge needed to optimize treatment strategies and improve outcomes for individuals living with T2DM.
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