Role of metformin in gynaecology and obstetrics
Abstract
Metformin raises much interest in the fields of gynaecology and obstetrics. This article discusses both the efficacy and safety of metformin in the management of polycystic ovary syndrome as well as in the prevention, treatment and follow-up of gestational diabetes. Recent observational data suggest that metformin may also exert positive effects as adjuvant therapy in some cancers, among which endometrial cancer and breast cancer.
La metformine suscite un réel intérêt dans le domaine de la gynécologie et de l’obstétrique. Cet article discute l’efficacité et la sécurité de la metformine dans la prise en charge des femmes avec un syndrome des ovaires micropolykystiques ainsi que dans la prévention, le traitement et le suivi d’un diabète gestationnel. Des données observationnelles récentes suggèrent également que la metformine pourrait jouer un rôle favorable comme traitement adjuvant dans certains cancers, dont ceux de l’endomètre et du sein.
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