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The top 50 cited publications in the field of vitamin B12 deficiency: A bibliometric analysis review

Aldakhil MD, Aldakhil HA, Istanboli A, Alamri RS, Aljuhani LI, Alahmed MA, Basalamah KA, Alzibali YM et al.

Journal of family medicine and primary care, 2025

Abstract

Background: Vitamin B12 deficiency is a significant nutritional concern linked to megaloblastic anemia and neurological complications, and high-quality research is essential to address these health issues effectively. While highly cited publications have substantial influence on the field, there remains a need to assess the methodological rigor, research trends, and quality of these impactful studies. This bibliometric analysis aims to evaluate the top 50 most-cited articles on Vitamin B12 deficiency, with a focus on identifying research gaps, trends, and areas for future investigation.

Methodology: A comprehensive literature search was conducted in the Web of Science database to identify the 50 most-cited articles on Vitamin B12 deficiency. Key terms included MeSH headings and keywords related to Vitamin B12 deficiency, and articles were included based on criteria such as peer-reviewed status, citation count, and focus on human subjects. Data extraction covered publication details (year, country, and journal), study characteristics (design, primary topic), and citation information. The selected articles were analyzed for authorship patterns, country contributions, study design distribution, and research topics to evaluate trends and gaps within the field.

Results: The analysis revealed a predominance of research originating from developed countries, with the US contributing 44% of the top-cited studies, followed by the UK at 16%. The most common study design was the review…

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