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Interventions for Hirsutism

van Zuuren EJ, Fedorowicz Z

JAMA, 2015

Abstract

CLINICAL QUESTION: What medical therapies are associated with greatest efficacy and fewest adverse events for treating hirsutism?

BOTTOM LINE: Oral contraceptive pills (OCPs) have been associated with improvement for mild hirsutism, as has flutamide (250 mg) twice daily and spironolactone for more severe cases. Finasteride and gonadotropin-releasing analogues are associated with inconsistent results and metformin is not associated with benefit.

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