Correlation Between Diabetes Prevalence and ICU/Hospital Stay Across Studies: A Systematic Review and Meta-Analysis
Abstract
Background: Diabetes mellitus elicits considerable concern regarding perioperative outcomes in cardiac surgery. This systematic review endeavors to elucidate the impact of diabetes on ICU and hospital length of stay (HLOS) following extracorporeal circulation (ECC) in cardiac surgery.
Methods: A comprehensive search of PubMed, Scopus, Embase, and the Cochrane Library was conducted, targeting clinical trials published between 2004 and 2024. The primary outcome assessed was the correlation between the proportion of diabetic patients and ICU length of stay. Secondary outcomes included the correlation between the proportion of diabetic patients and HLOS, as well as the relationships between the proportion of diabetic patients and ICU length of stay with mean age, sex distribution, and BMI. Weighted correlation analyses were employed.
Results: Thirteen studies (1,588 patients) were included. The weighted correlation between the proportion of diabetic patients and ICU length of stay was -0.176 (p=0.574, power=0.96), indicating a weak and non-significant correlation. Nine studies (925 patients) analyzed HLOS, revealing a weak but statistically significant negative correlation (-0.2545, p=0.002). The mean age of patients was 64.70 years, which did not significantly affect ICU length of stay (coefficient = 0.0652, p=0.506). Sex distribution showed 24.98% female and 75.02% male participants, with significant differences (chi-square = 38.764, p<0.01). BMI analysis showed a mean BMI of…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 1,588 participants or records.
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