Effect of hysteroscopic metroplasty on reproductive outcomes in women with septate uterus. Systematic review and meta-analysis
Abstract
OBJECTIVE
The aim of this systematic review with meta-analysis is to evaluate the impact of hysteroscopic metroplasty on adverse reproductive outcomes such as miscarriage, preterm birth and fetal malpresentation in patients with history of infertility or previous poor obstetrical outcomes.
DATA SOURCES
A systematic electronic search from inception each database up to April 2021 including the following databases was conducted: PubMed-MEDLINE, EMBASE, Web of Science, The Cochrane Library, the CGF Specialized Register of Controlled Trials, Google Scholar and trial registries. A combination of the following keywords was used: `uterine septum´, `septate uterus´, `congenital uterine malformation´, `class 2 uterus´, `class V uterus´, `metroplasty´, `hysteroscopic´, `pregnancy´, `clinical pregnancy´, `ongoing pregnancy´, `miscarriage´, `live birth´, `preterm birth´, `cesarean section´, `cesarean delivery ´ and `fetal malpresentation´.
METHODS OF STUDY SELECTION
Studies comparing reproductive outcomes between women undergoing hysteroscopic resection of the uterine septum and those with expectant management were included. Eligible population consisted of infertile women, women with poor obstetrical history or women without previous pregnancy failures and a diagnosis of septate uterus.
TABULATION, INTEGRATION AND RESULTS
The systematic electronic search retrieved 1076 studies, after duplicates elimination, 688 titles and abstracts were screened and 55 assessed for eligibility. Eleven…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 1,589 participants or records.
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