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Inhibitors of Efflux Pumps in Pseudomonas a eruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin

Thomas E. Renau, Roger Léger, Eric M. Flamme, Joan C. Sangalang, Miles W. She, Rose Yen, Carla L. Gannon, David C. Griffith et al.

Journal of Medicinal Chemistry, 1999

261 citations

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTInhibitors of Efflux Pumps in Pseudomonas aeruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial LevofloxacinThomas E. Renau, Roger Léger, Eric M. Flamme, Joan Sangalang, Miles W. She, Rose Yen, Carla L. Gannon, David Griffith, Suzanne Chamberland, Olga Lomovskaya, Scott J. Hecker, Ving J. Lee, Toshiharu Ohta, and Kiyoshi NakayamaView Author Information Microcide Pharmaceuticals Inc., 850 Maude Avenue, Mountain View, California 94043, and New Product Research Laboratories I, Daiichi Pharmaceutical Company Ltd., 1-16-13, Kita-Kasai, Edogawa, Tokyo 134-8630, Japan Cite this: J. Med. Chem. 1999, 42, 24, 4928–4931Publication Date (Web):November 10, 1999Publication History Received8 September 1999Published online10 November 1999Published inissue 2 December 1999https://pubs.acs.org/doi/10.1021/jm9904598https://doi.org/10.1021/jm9904598rapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views2031Altmetric-Citations201LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is…

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