A Randomized Double-blind Controlled Trial Study on the Antagonistic Effect of Composite Polyphenols on Health Damage Caused by Environmental Pollutants
Abstract
The study attempts to conduct randomized controlled trials to understand whether daily exposure to environmental pollutants can cause harm to human health, explore whether the intake of composite polyphenols can alleviate potential health hazards caused by environmental pollutants, and provide scientific basis for the prevention and treatment of health hazards caused by environmental pollutant exposure.
Conditions: Intestinal Functional Disorder, Inflammation.
Primary outcome: Fecal microplastics (MPs) levels as assessed by Py-GC/MS; Fecal metagenomic sequencing as sequenced using the Illumina NovaSeq/HiSeq Xten platform; Blood Metabolomics as assessed by UPLC-TripleTOF; Inflammatory cytokines as assesed by Luminex technology; Blood glucose indicators as assessed by the Hitachi 7180 fully automatic biochemical analyzer; Blood lipid indicators as assessed by the Hitachi 7180 fully automatic biochemical analyzer; Routine blood examination as assessed by the Dima DH36X fully automatic blood cell analyzer.
Enrollment: 98 participants.
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 98 participants or records.
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