Evidence Hub

Microplastics and nanoplastics in clinical dentistry and orthodontics: leaching, health implications, and future directions: a narrative review

Umrai Shariff K, Le A, Goodwin-Loughton E, Chung M, Ali A, Farella M, Venugopal A

Progress in orthodontics, 2025

10 citations

Abstract

This narrative review critically summarizes that microplastics and nanoplastics have been found in many different environments, including water and food, raising concerns on their possible harm to human health. Previous research indicates that microplastics may cause inflammation and tissue damage; however, the full extent of their health risks remains uncertain. Given the long-term use of plastic-based orthodontic appliances such as aligners, retainers, and widespread usage of adhesives, the potential release of microplastics and nanoplastics during routine wear and mechanical stress warrants thorough investigation to ensure patient safety and long-term biocompatibility. The literature search conducted for this review was structured but non-systematic, with no formal risk-of-bias evaluation. This review aimed to critically evaluate the impact of microplastics and nanoplastics on human health, with a focus on their relevance to orthodontics. The review also aimed to identify possible gaps in current research, particularly regarding the quantification of microplastic leakage from orthodontic appliances and their possible long-term effects. Current evidence highlights a clear need for more targeted research to inform and improve safety standards regarding microplastics and plastic usage in orthodontic and dental practice.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free