Food packaging-derived endocrine disruptors and breast cancer nutrition: dietary exposure, estrogen signaling, and survivorship implications
Abstract
Food packaging and other food contact materials are increasingly recognized as sources of dietary chemical exposure. Among the compounds that may migrate from packaging into foods, several classes are relevant to breast cancer nutrition because they can act as endocrine-disrupting chemicals, including bisphenols, phthalates, per- and polyfluoroalkyl substances, and selected non-intentionally added substances generated during food-contact material manufacture or use. These exposures do not replace established nutritional determinants of breast cancer outcomes, such as dietary quality, body weight, physical activity, and metabolic health. Rather, they represent an overlooked dimension of the food environment that may intersect with estrogen signaling, adipose inflammation, oxidative stress, epigenetic regulation, and treatment-related survivorship needs. Evidence linking packaging-derived endocrine disruptors to breast cancer remains heterogeneous and is strongest for mechanistic plausibility and exposure biology, while epidemiologic associations vary across compounds, timing of exposure, biomarkers, and tumor subtypes. This Mini Review synthesizes current evidence on food packaging-derived endocrine disruptors in relation to breast cancer nutrition, with emphasis on dietary exposure pathways, estrogen-related mechanisms, and practical survivorship implications. We propose that nutrition guidance for breast cancer survivors should include low-burden strategies to reduce…
Read the paper
Related studies
- Green Chemistry: A Framework for a Sustainable Future
- Nano/micro-plastic, an invisible threat getting into the brain
- Emerging contaminants antibiotic resistance genes and microplastics in the environment: Introduction to 21 review articles published in CREST during 2018–2022
- Water Resources and Sustainable Development
- Nano- and microplastics in the workplace
- Water Enclosure and World-Literature: New Perspectives on Hydro-Power and World-Ecology
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.