Effects of Radioactive Cesium-Containing Water on Mice
Abstract
To investigate the transgenerational effect of chronic low-dose-rate internal radiation exposure after the Fukushima Nuclear Power Plant accident in Japan, every generation of mice was maintained in a radioisotope facility with free access to drinking water containing 137CsCl (100 Bq/ml). Descendent mice were assessed for γ-H2AX foci in hepatocytes, the micronucleus test and chromosome aberration analysis in bone marrow cells, DNA mutations in the liver, tumorigenicity in the lung, oxidative stress in blood plasma, and metabolome analysis in the heart.
How strong is the evidence?
Evidence Hub reads this as a book / chapter, done in animal, not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Green Chemistry: A Framework for a Sustainable Future
- Nano/micro-plastic, an invisible threat getting into the brain
- Emerging contaminants antibiotic resistance genes and microplastics in the environment: Introduction to 21 review articles published in CREST during 2018–2022
- Water Resources and Sustainable Development
- Nano- and microplastics in the workplace
- Water Enclosure and World-Literature: New Perspectives on Hydro-Power and World-Ecology
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.