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Exposure to micro- and nano-plastics: From human internal burden to systems-level health-risk interpretation

Tu C, Yang J, Liao J, Hu R, Feng Y, Wu D, Xia Y, Wang D et al.

iMeta, 2026

Abstract

Micro- and nano-plastics (MNPs) can enter the human body through inhalation, ingestion, contact with consumer products, and iatrogenic routes. The clinical relevance of MNP exposure should be interpreted at three levels: barrier interaction, cellular stress, and system-level disruption, with key mechanisms including oxidative stress, mitochondrial dysfunction, and chronic inflammation.

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