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Comment on Sofi et al. pH of Drinking Water Influences the Composition of Gut Microbiome and Type 1 Diabetes Incidence. Diabetes 2014;63:632–644

Yong-Ge Zhao, K. Tarbell

Diabetes, 2015

10 citations

Abstract

We read with interest the report by Sofi et al. (1) in Diabetes . This article is of practical interest to many groups who use the nonobese diabetic (NOD) mouse model. As this group observed, we have also observed that mice that are ordered from The Jackson Laboratory tend to get diabetes sooner than those bred in National Institutes of Health facilities. The results in this article suggest this is partly due to the use of acidic (pH 3.0–3.2) water. If true, it would be a …

How strong is the evidence?

Evidence Hub reads this as a editorial / letter, done in animal, not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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