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Effects of Mantram Repetition on Spiritual Well-Being: A Systematic Review and Meta-Analysis

Kuhn ALR, Schneider JK, Easton SD, Abdullahi SG, Willis DG

Journal of integrative and complementary medicine, 2025

Abstract

Background: Spiritual well-being is an essential component of whole-person care and is increasingly recognized in various clinical disciplines as positively affecting mental health. Mantram repetition (MR) is an intervention rooted in Eastern spiritual traditions that has been shown to have clinical benefits, including reduction of psychological distress, among individuals with chronic psychological conditions. The central aim of this meta-analysis was to examine the effects of MR on spiritual well-being. Methods: Fifteen databases were searched from their inception year to July 19, 2023. Two independent reviewers extracted and coded data from randomized or quasi-experimental studies with comparison groups, conducted to test MR, measured spiritual well-being, and reported their study in English. Coded data included study quality indicators which were used in moderator analyses. Results: After the initial and updated searches and removal of duplicates, we reviewed 2,072 articles; seven studies met inclusion criteria with a total sample size of 556 (MR = 272, comparison = 284). Overall, MR had a positive effect on spiritual well-being with a pooled effect size of 0.535 with Hartung-Knapp-Sidik-Jonkman adjusted 95% confidence intervals of 0.18 and 0.89 (p = 011). Using moderator analyses, we examined the effect of the quality indicators and intervention characteristics on effect size; only session length was significant. Longer MR intervention sessions (i.e., 90 min) had…

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