Interventions for preventing dengue: a mapping review
Abstract
Background: Dengue remains a pressing global health challenge, particularly in low- and middle-income countries (LMIC). Despite a growing volume of research on prevention strategies, there is a notable lack of consolidated, high-level research capturing the full scope of existing knowledge. The current evidence landscape is fragmented, with studies varying widely in design, focus, and quality. A structured map that includes both primary studies and systematic reviews is urgently needed. Such evidence and gap maps (EGMs) serve as a decision-support tool for funders, policymakers, and researchers by identifying where research exists and where future investments are most needed.
Objectives: To: 1. comprehensively identify the published literature on dengue prevention strategies; 2. critically appraise systematic reviews; 3. present the findings of objectives 1 and 2 in a single evidence gap map; and 4. identify critical knowledge gaps to inform future primary studies and systematic reviews.
Search methods: We searched MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCO), Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Reviews (CDSR) in the Cochrane Library, and LILACS (BIREME) on 6 August 2025. We did not apply any date or language restrictions to the searches.
Selection criteria: We included randomised controlled trials (RCTs), quasi-randomised trials, non-randomised studies of interventions (NRSIs) and systematic reviews. NRSIs had to have a…
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