Meta-analysis of gatifloxacin and levofloxacin in treatment of urinary tract infection
Abstract
Objectiive Evaluation of gatifloxacin and levofloxacin in the treatment of urinary tract infection clinical safety, effectiveness, efficiency, and cost of treatment. Methods Retrieving from January 1998 to April 2016 in Pub Med, Cochrane Library, Chinese Journal Full-text Database(CNKI), Wanfang Database, Chinese Science and Technology Journal Full-text Database(VIP), Chinese Biomedical Literature Database(CBM) published on plus gatifloxacin and levofloxacin in the treatment of urinary tract infections in the literature, according to Cochrane systematic review methods, using Rev Man 4.2.10 Meta-analysis software. Results Document 17 included, a total of 1 348 cases; the effectiveness of gatifloxacin treatment of urinary tract infection was significantly higher than levofloxacin [RR=2.01, 95% CI(1.44, 2.79)], treatment and adverse indifference [RR=0.76, 95% CI(0.50, 1.17), P=0.22], but the cost of gatifloxacin treatment of urinary tract infection was significantly lower than the effect of levofloxacin. Conclusion Currently urinary tract infection treatment regimens, though the effectiveness of gatifloxacin was higher than levofloxacin, but levofloxacin more cost-effectiveness advantage.
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