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PTEN: Regulation, Signalling and Targeting in Cancer

Kotelevets L, Scott MGH, Chastre E

Cancers, 2026

Abstract

PTEN (phosphatase and tensin homolog deleted on chromosome ten)/MMAC1 (mutated in multiple advanced cancers) was discovered by two groups in 1997 as a novel tumor suppressor gene located at chromosome 10q23 [...].

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