(414) A Consensus on the Management of Premature Ejaculation
Abstract
Abstract Introduction To provide an evidence based consensus on the diagnosis and management of premature ejaculation (PE). The authors take issue with the advice to use off label treatments, such as daily selective serotonin reuptake inhibitors treatment, favoring on-demand dapoxetine. There is increasing evidence for the use of PDE5 inhibitors which are superior to a placebo for the treatment of PE. A recent meta-analysis of international PE guidelines supports the need for research to investigate the association of PE with erectile dysfunction (ED), prostatitis and thyroid disease, and supports the early use of PDE5 inhibitors either alone or in combination with dapoxetine or psychosexual interventions. Topical agents and non-pharmacological treatments also have a place, with new agents in the pipeline. Objective General practitioners tend to rely on local guidance, and international guidelines which are heterogeneous, indicating diagnostic and therapeutic approaches that are often inconsistent. Different international and local guidelines on PE are currently in force. They have several similarities but also many differences that reflect prevalence rates and cultural variations. The latter appear particularly evident when analyzing the definitions of PE and the recommendations on the management of the patient with PE. The aim of this position statement is to improve the management of PE. Methods A comprehensive review of Local, National and International guidelines was…
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