PD50-04 efficacy and tolerability of dapoxetine and sertraline for the treatment of chinese patients with premature ejaculation
Abstract
You have accessJournal of UrologySexual Function/Dysfunction: Medical, Hormonal & Non-surgical Therapy II1 Apr 2016PD50-04 EFFICACY AND TOLERABILITY OF DAPOXETINE AND SERTRALINE FOR THE TREATMENT OF CHINESE PATIENTS WITH PREMATURE EJACULATION Lin Yang and Dalin He Lin YangLin Yang More articles by this author and Dalin HeDalin He More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2794AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Premature ejaculation (PE) is one of the most prevalent male sexual dysfunction, and can have a detrimental effect on self-confidence and on interpersonal relationships. Pharmacotherapy with selective serotonin reuptake inhibitor (SSRI) represents the most efficacious treatment option for PE. In this paper we compared the efficacy and tolerability of dapoxetine and sertraline pharmacotherapy for the treatment of PE. METHODS From January 2015 to June 2015, a total of 117 patients with PE seeking treatment in our hospital were randomly assigned (2:1) to receive either dapoxetine 30 mg 1-3 h before planned sexual intercourse (n=78) or sertraline 50 mg once daily for 1 month (n=39). Intravaginal ejaculatory latency time (IELT), clinical global impression of change (CGIC) score, Premature Ejaculation Pro?le (PEP) and treatment-emergent adverse events (TEAEs) were recorded as outcomes. RESULTS Both groups…
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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 117 participants or records.
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