A Prospective Study Comparing Paroxetine Alone Versus Paroxetine Plus Sildenafil in Patients With Premature Ejaculation
Abstract
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Dec 2002A Prospective Study Comparing Paroxetine Alone Versus Paroxetine Plus Sildenafil in Patients With Premature Ejaculation ANDREA SALONIA, TOMMASO MAGA, RENZO COLOMBO, VINCENZO SCATTONI, ALBERTO BRIGANTI, ANDREA CESTARI, GIORGIO GUAZZONI, PATRIZIO RIGATTI, and FRANCESCO MONTORSI ANDREA SALONIAANDREA SALONIA , TOMMASO MAGATOMMASO MAGA , RENZO COLOMBORENZO COLOMBO , VINCENZO SCATTONIVINCENZO SCATTONI , ALBERTO BRIGANTIALBERTO BRIGANTI , ANDREA CESTARIANDREA CESTARI , GIORGIO GUAZZONIGIORGIO GUAZZONI , PATRIZIO RIGATTIPATRIZIO RIGATTI , and FRANCESCO MONTORSIFRANCESCO MONTORSI View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64174-2AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We compared the efficacy of paroxetine alone and combined with sildenafil in patients complaining of premature ejaculation. Materials and Methods: Enrolled in this study were 80 consecutive potent men 19 to 47 years old (mean age 34) with premature ejaculation but without any obvious organic cause. Pretreatment evaluation included a history, self-administration of the International Index of Erectile Function (IIEF) questionnaire, physical examination and the Meares-Stamey test to exclude genital tract infection. The initial 40 patients received 10 mg. paroxetine daily for 21 days and then 20 mg. as needed, that is 3 to 4…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 80 participants or records.
Read the paper
Related studies
- Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial
- Clinical characteristics and risk factors associated with COVID-19 severity in patients with haematological malignancies in Italy: a retrospective, multicentre, cohort study
- A randomized, controlled trial of oral propranolol in infantile hemangioma
- Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study
- Increased physical activity improves sleep and mood outcomes in inactive people with insomnia: a randomized controlled trial
- COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.