The Potential of Once-Daily Tadalafil in Enhancing Erectile Dysfunction Recovery in Patients with Diabetes Mellitus: An Updated Review
Abstract
Erectile dysfunction (ED) is a common chronic complication in men with diabetes mellitus (DM), with a prevalence significantly higher than in the general population. A literature review was conducted using PubMed, ScienceDirect, Cochrane Library, and Google Scholar, focusing on articles from 2013–2024. Inclusion criteria were clinical studies, meta-analyses, and systematic reviews discussing daily tadalafil use in diabetic men with ED. Most studies show that tadalafil once a day significantly improves IIEF scores, sexual satisfaction, and is well tolerated. Some studies also report long-term vascular benefits and improved endothelial function. Daily tadalafil offers potential as a sustainable and effective ED treatment in DM patients, with possible vascular advantages. Further long-term randomized studies are needed to support its inclusion in clinical guidelines.
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