(026) penile rehabilitation after radical prostatectomy using LOW-intensity shockwave therapy for erectile function: late results findings from a randomized clinical trial
Abstract
There is still few evidence to support the use of low-intensity extracorporeal shockwave therapy (LiESWT) in the management of erectile dysfunction (ED) after radical prostatectomy (RP).
The aim of this study is to assess the long-term results of LiWEST as a penile rehabilitation method in patients who underwent RP.
This is an assessment of the late results outcomes of our previous clinical trial registered in ReBEC (ensaiosclinicos.gov.br) RBR-85HGCG. Patients were randomized in two groups with 2 parallel arms and an allocation ratio of 1:1. The control group received tadalafil 5 mg/day, while the experimental group were submitted to tadalafil 5 mg/day plus 2400 shocks/session-week distributed on 4 different penile regions across 8 weeks of treatment. Both groups started the penile rehabilitation after the removal of the transurethral catheter. Sexual function was assessed by IIEF-5 score.
Among 77 patients included in our previous analysis, 35 patients were reassessed after a median follow-up of 45 months (42-50 months; CI 95%). 17 of them had to be excluded from the analysis for biochemical recurrence and/or new interventions. Remaining 7 and 11 patients in the experimental and control group, respectively. The final mean IIEF-5 score between experimental and control groups showed a difference in favor of the LiWEST group, not statistics significantly (18.85, SD 5.66, 95% CI 13.61-24.1 x 16.63, SD 5.48, 95%CI 12.9-20.31; respectively; p = 0.42). Subgroup analysis in…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 77 participants or records.
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