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Rapid Pain Reduction Following a Multimodal Physiotherapy Protocol in a Retrospective Case Series of Patients With Persistent Scrotal Content Pain

C. Mendias, T. Awan

Cureus, 2026

25 participants · 1 citation

Abstract

Introduction: Scrotal content pain (SCP) is a clinically significant condition that can substantially impair quality of life. The causes of SCP are heterogeneous and may include urologic, neuropathic, musculoskeletal, vascular, inflammatory, referred, and psychosocial contributors. In some patients, dysfunction of the lower abdominal wall, inguinal canal, or pelvic floor may contribute to regional nerve irritation and persistent pain. The objective of this retrospective case series was to describe pain and quality-of-life outcomes following a multimodal physiotherapy protocol in men with persistent SCP. Methods: Twenty-eight men with persistent SCP, with a mean age of 42.1 years (95% CI, 36.3 to 47.9), who completed the four-week protocol and had complete baseline and post-treatment outcome data were included. The protocol consisted of four weekly sessions of class IV laser therapy, dry needling, pulsed electromagnetic field therapy, manual therapy, progressive therapeutic exercise, and daily oral tadalafil. Pain was measured before and after each session using a 10-cm visual analog scale (VAS). Physical and mental health were assessed before treatment and after the final session using the Patient-Reported Outcomes Measurement Information System (PROMIS) Global-10. Available follow-up data were reviewed for symptom recurrence and additional treatment. Results: Mean VAS pain decreased from 8.0 cm (95% CI, 7.8 to 8.2) before the first treatment session to 3.0 cm (95% CI, 2.6…

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