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Research on the Mechanism of Action of Traditional Chinese and Western Medicine and the Course of Treatment for Shenrongbian Pills in the Treatment of Impotence and Premature Ejaculation

Chunlei Chen, Wei Yang, Bei Zhang, Zheng Li

Advances in Precision Medicine, 2025

160 participants

Abstract

Objective: To investigate the clinical efficacy, mechanism of action of traditional Chinese and Western medicine, and reasonable treatment regimen of Shenrongbian pills in the treatment of impotence and premature ejaculation caused by kidney-Yang deficiency. Methods: A total of 160 patients with impotence and premature ejaculation caused by kidney-Yang deficiency admitted to our hospital from January 2023 to January 2024 were randomly divided into an observation group (80 cases) and a control group (80 cases). The observation group was treated with Shenrongbian pills; the control group was treated with sildenafil citrate tablets combined with dapoxetine. The International Index of Erectile Function (IIEF-5), intravaginal ejaculatory latency time (IELT), traditional Chinese medicine kidney-Yang deficiency syndrome score, overall clinical response rate, and safety were compared between the two groups before and after treatment. Results: There was no significant difference in the IIEF-5 scores and IELT between the two groups before treatment (P > 0.05). After 3 months and 6 months of treatment, both indicators improved significantly in both groups (P 0.05). After 3 and 6 months of treatment, the traditional Chinese medicine (TCM) syndrome scores in the observation group were significantly lower than those in the control group (P 0.05). After 6 months of treatment, the overall response rate in the observation group was 93.75%, significantly higher than the 81.25% in the control…

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