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Successful Pregnancy in Chronic Obstructive Pulmonary Hypertension Secondary to Pulmonary and Cardiac Hydatid Cysts: A Case Report

Farnaz Ahmadi, R. Parnia, Bahamin Astani, M. Keshmiri, Shakiba Khodadad, Hakimeh Sheikhzadeh, Z. Daneshmandi, F. Ansari et al.

Research in heart yield and translational medicine, 2026

Abstract

Highlights

Pregnancy is typically contraindicated in women with pulmonary hypertension (PH) due to severe mortality risks.A 31-year-old woman with PH, secondary to previous hydatid cysts, conceived against medical advice while on medical therapy. She successfully delivered via emergency C-section at 37 weeks.Her case highlights those high-risk pregnancies complicated by PH can be successfully managed through prompt, multidisciplinary care at a specialized tertiary center.

Background

Pregnancy in women with pulmonary hypertension (PH) is contraindicated because of high mortality rates associated with physiological changes, particularly in the peripartum and postpartum periods. Termination is recommended early if pregnancy occurs. Consequently, clinical experience with continued pregnancy in patients with PH is scarce.

Case Presentation

A 31-year-old woman was diagnosed with multiple bilateral pulmonary and right ventricular hydatid cysts. After surgical and pharmacologic treatments, she developed PH due to pulmonary artery obstruction 8 years later. Because of her condition, she was ineligible for surgery and received medical therapy, including tadalafil, bosentan, and eplerenone. After 3 years, she conceived despite advice to avoid pregnancy. At 37 weeks' gestation, she underwent successful emergency cesarean delivery because of maternal dyspnea and tachycardia.

Conclusion

Prompt treatment and regular follow-up in a tertiary care center using a multidisciplinary approach are…

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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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