Scrotal Abscess Caused by Ignavigranum ruoffiae: A Case Report and Literature Review
Abstract
Abstract Background: Ignavigranum ruoffiae is a rare catalase-negative, facultatively anaerobic Gram-positive coccus. Published human infections remain exceptionally uncommon and have mainly involved localized suppurative disease at non-genitourinary sites. To our knowledge, scrotal involvement has not been reported previously. Case Report: A 63-year-old man presented with a 2-day history of progressive painful swelling of the left scrotum and inguinal region. Systemic inflammatory findings were not striking on admission, with a white blood cell count of 9.27 × 10^9/L and a procalcitonin level of 0.08 ng/mL. Scrotal ultrasonography demonstrated a 21 × 12 × 18 mm heterogeneous lesion in the left inguinal-scrotal region. Empirical intravenous levofloxacin was started after admission. On hospital day 2, the patient developed a transient fever of 38.0 °C, and the lesion ruptured spontaneously. Needle aspiration drainage yielded approximately 5 mL of gray-white pus. Culture showed pure growth of small gray-white colonies on sheep blood agar. Gram staining demonstrated Gram-positive coccoid organisms arranged in pairs and short chains. The isolate was identified as I. ruoffiae by MALDI-TOF MS using a Bruker microflex LT/SH system (score 2.40) and was further confirmed by 16S rRNA gene sequencing. MICs were generated using the VITEK 2 system. The isolate showed low MICs for beta-lactams and in vitro activity of levofloxacin, although categorical interpretation was made cautiously…
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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