Bone Sparing by Calcium Salts With and Without Extra Phosphorus
Abstract
Osteoporosis causes bones to weaken and break more easily. Calcium and phosphorus are two minerals that are essential for normal bone formation. Unfortunately, calcium salts commonly prescribed in anti-osteoporosis treatment bind phosphorus from food and restrict phosphorus available for bone building. Teriparatide is a drug that reduces the risk of fractures by increasing bone thickness and strength. Vitamin D is also necessary for strong bones and teeth. The purpose of this study is to evaluate the bone-building effectiveness of two calcium supplements, one with a source of phosphorus and one without, in combination with teriparatide and vitamin D in women with osteoporosis.
Conditions: Osteoporosis, Osteopenia.
Primary outcome: Lumbar Spine and Hip BMD, Measured as Grams Per Square Centimeter.; Bone Mineral Density (BMD) Under Treatment With an Anabolic Agent (Teriparatide)..
Enrollment: 241 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 241 participants or records.
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