Redefining vitamin D insufficiency
Abstract
Vitamin D deficiency causes secondary hyperparathyroidism which can lead to osteomalacia, irreversible bone loss,1 and increased risk of fracture.2,3 Vitamin D deficiency is not well characterised and varying 25-hydroxyvitamin D (25[OH]D) thresholds have been used.4,5 We evaluated the effect on blood concentrations of parathyroid hormone (PTH) by increasing 25(OH)D levels above 25 nmol/L with vitamin D therapy.
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