Association of Different Levels of Vitamin D Deficiency and Hip Fracture in Indian Population: A Cross-sectional Study
Abstract
Abstract Introduction: Hip fractures represent a major public health problem in India, associated with significant morbidity, mortality, and socioeconomic burden. Vitamin D deficiency, highly prevalent in the Indian population, is a modifiable risk factor for osteoporosis, muscle weakness, falls, and fragility fractures. While the association between hypovitaminosis D and hip fractures is well established, limited Indian data exist examining fracture patterns across different severities of Vitamin D deficiency. The study is to evaluate the association between varying levels of serum Vitamin D deficiency and types of hip fractures in the Indian population. Materials and Methods: This hospital-based cross-sectional observational study was conducted in the Department of Orthopaedics, School of Medical Sciences and Research, Sharda University, Greater Noida, from April 2024 to November 2025. Fifty patients aged >50 years (females) and >60 years (males) presenting with low-energy hip fractures were included. Serum 25-hydroxyvitamin D levels were measured using a VITROS 5600 dry chemistry autoanalyzer. Vitamin D status was categorized as severe deficiency (30 ng/mL). Statistical analysis was performed using the Statistical Package for the Social Sciences v22 with the Chi-square test and analysis of variance. Results: The majority of patients were aged 70–79 years (52%). Intertrochanteric fractures were the most common fracture type (60%), followed by neck of femur fractures (34%).…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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