Ocular Availability in Human Tears After Topical Administration of 1.5% Levofloxacin Compared to Active Comparators
Abstract
The primary objective of this study is to compare the concentration in human tears of levofloxacin and the active comparators at 15 minutes, 2,6, 12, and 24 hours after instillation of a single drop of medication.
Conditions: Healthy.
Primary outcome: Concentration of levofloxacin, moxifloxacin or gatifloxacin in tears.
Enrollment: 72 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 72 participants or records.
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