The Relation of Osteoporotic Vertebral Fractures and Sarcopenic Characteristics on the Occurrence of Complications: A Systematic Review
Abstract
Study design: Systematic review.
Purpose: As the number of elderly increases, age-related changes of body composition like osteoporosis and sarcopenic muscle changes contribute to higher morbidity, less quality of life and higher health care costs. Data on the effect of muscle atrophy on osteoporotic vertebral fractures is limited. We systematically reviewed the current literature for the influence of preexisting degenerative muscle changes in patients with OVF on the occurrence of complication during and after treatment.
Methods: A systematic literature review adherent to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines was performed using the Web of Science and Medline databases. We considered English and German articles from January 1990 to December 2022. Inclusion criteria covered patients with OVF and muscle degeneration with complications during and after treatment. Included trials were cohort studies and case series.
Results: Eight Studies were included in this systematic review. One studied the role of degenerated paravertebral muscle during conservative treatment. One article analysed the influence of sarcopenia after dorsal instrumentation in patients with OVF, another the effects of muscle degeneration after dorsal instrumentation or kyphoplasty. The other studies evaluated complications after percutaneous vertebroplasty or kyphoplasty. Seven studies described an increased risk for subsequent fracture following OVF…
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Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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