Do calcium, vitamin D, and calcium with vitamin D supplementation reduce the risk of fracture in community-dwelling older adults?
Abstract
Calcium and vitamin D supplements, together or alone, do not reduce fracture risk in communitydwelling adults older than 50 years, regardless of dose, sex, fracture history, dietary calcium intake, or baseline serum vitamin D level (SOR: A, consistent systematic reviews of randomized controlled trials [RCTs]). For postmenopausal women, the United States Preventive Services Task Force (USPSTF) recommends against vitaminD supplements of 400 IU or less and calcium supplements of 1,000 mg or less and found insufficient evidence to assess the benefit versus risks of higher doses or for treatment the of men and premenopausal women (SOR:A, systematic review of RCTs and USPSTF recommendation). Copyright © 2019 by Family Physicians Inquiries Network, Inc. DOI 10.1097/EBP.0000000000000649
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